| Gene Information | |
|---|---|
| Gene Name | RFWD2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 731 |
| Protein Names | E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1) (RING finger and WD repeat domain protein 2) (RING finger protein 200) (RING-type E3 ubiquitin transferase RFWD2) |
| Target Name | e3 ubiquitin-protein ligase cop1 |
| Target Type | Successful target |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8NHY2 |
| Gene Card | COP1 |
| Uniprot ID | Q8NHY2 |
| Pfam | PF00400 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed at low level. Expressed at higher level in testis, placenta, skeletal muscle and heart. {ECO:0000269|PubMed:12615916, ECO:0000269|PubMed:15103385}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002990(Rat);0.047368(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5HQG (X-ray 2.00A ) 5IGQ (X-ray 3.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus speckle. Cytoplasm. Note=In the nucleus, it forms nuclear speckles. |
| Mouse PG classification | NA |
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