| Gene Information | |
|---|---|
| Gene Name | VPS50 |
| Organism | Homo sapiens (Human) |
| Gene Length | 964 |
| Protein Names | Syndetin (Coiled-coil domain-containing protein 132) (EARP/GARPII complex subunit VPS50) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000004766 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96JG6 |
| Gene Card | VPS50 |
| Uniprot ID | Q96JG6 |
| Pfam | PF10474; PF10475 |
| In ASD | no |
| Allosteric Prediction | no (-1.211203525) |
| Ortholog in Animals | Alpaca_ VPS50 ( ortholog_one2one ) Dog_ VPS50 ( ortholog_one2one ) GuineaPig_ VPS50 ( ortholog_one2one ) Macaque_ VPS50 ( ortholog_one2one ) Mouse_ Vps50 ( ortholog_one2one ) Pig_ VPS50 ( ortholog_one2one ) Rat_ Vps50 ( ortholog_one2one ) Rabbit_ VPS50 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous, with higher expression in brain and skeletal muscle. {ECO:0000269|PubMed:21472204}. |
| Pharmacological Animal Models | 0.013343(Chimpanzee);0.014650(Mouse);0.025445(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Recycling endosome {ECO:0000269|PubMed:25799061}. Membrane {ECO:0000250|UniProtKB:F1LSG8}. Note=Associates with membranes in an EIPR1-dependent manner. {ECO:0000250|UniProtKB:F1LSG8}. |
| Mouse PG classification | NA |
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