Gene Information
Gene NameRFC4
OrganismHomo sapiens (Human)
Gene Length363
Protein NamesReplication factor C subunit 4 (Activator 1 37 kDa subunit) (A1 37 kDa subunit) (Activator 1 subunit 4) (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37)
Target NameNA
Target TypeNA
Gene Age>4290 ( ENSG00000163918 )
Evolutionary StageEukaryota
AlphaFoldDBP35249
Gene CardRFC4
Uniprot IDP35249
PfamPF00004; PF08542
In ASDno
Allosteric Predictionno (-0.006705842)
Ortholog in AnimalsAlpaca_ RFC4 ( ortholog_one2one )
Dog_ RFC4 ( ortholog_one2one )
GuineaPig_ RFC4 ( ortholog_one2one )
Macaque_ RFC4 ( ortholog_one2one )
Mouse_ Rfc4 ( ortholog_one2one )
Pig_ RFC4 ( ortholog_one2one )
Rat_ Rfc4 ( ortholog_one2one )
Rabbit_ RFC4 ( ortholog_one2one )
OhnologsNA
ParalogsRFC3, RFC5, RFC2
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.178811(Rat);0.113625(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 6VVO  (EM  3.40A  7Z6H  (EM  3.59A 
DBSNP rs2066497 
Subcellular location [CC]Nucleus {ECO:0000305}.
Mouse PG classificationNA
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