| Gene Information | |
|---|---|
| Gene Name | REV3L |
| Organism | Homo sapiens (Human) |
| Gene Length | 3130 |
| Protein Names | DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (hREV3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000009413 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | NA |
| Gene Card | REV3L |
| Uniprot ID | O60673 |
| Pfam | PF00136; PF03104; PF15735; PF14260 |
| In ASD | no |
| Allosteric Prediction | no (-0.508345612) |
| Ortholog in Animals | Alpaca_ REV3L ( ortholog_one2one ) Dog_ REV3L ( ortholog_one2one ) GuineaPig_ REV3L ( ortholog_one2one ) Macaque_ REV3L ( ortholog_one2one ) Mouse_ Rev3l ( ortholog_one2one ) Pig_ REV3L ( ortholog_one2one ) Rat_ Rev3l ( ortholog_one2one ) Rabbit_ REV3L ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NEXMIF, POLD1, POLA1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002895(Rat);0.052174(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3ABD (X-ray 1.90A ) 3ABE (X-ray 2.60A ) 3VU7 (X-ray 2.80A ) 4EXT (X-ray 1.90A ) 4GK0 (X-ray 2.70A ) 4GK5 (X-ray 3.21A ) 5O8K (X-ray 1.80A ) 6BC8 (X-ray 1.68A ) 6BCD (X-ray 1.43A ) 6BI7 (X-ray 2.80A ) 6EKM (X-ray 2.76A ) 6KEA (X-ray 2.35A ) 6WS0 (X-ray 2.24A ) 6WS5 (X-ray 2.47A ) |
| DBSNP | rs1053911 rs3218579 rs3218598 rs3218593 rs17539588 rs458017 rs3218600 rs462779 rs3218578 rs3218597 rs3218595 rs17539616 rs3218572 rs1053913 rs3218582 rs3218585 rs17539644 rs17539651 rs3218599 rs3218604 rs3218606 rs17539692 rs17510963 rs3218592 rs3204953 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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