Gene Information
Gene NameREV1
OrganismHomo sapiens (Human)
Gene Length1251
Protein NamesDNA repair protein REV1 (EC 2.7.7.-) (Alpha integrin-binding protein 80) (AIBP80) (Rev1-like terminal deoxycytidyl transferase)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000135945 )
Evolutionary StageCellular_organisms
AlphaFoldDBQ9UBZ9
Gene CardREV1
Uniprot IDQ9UBZ9
PfamPF16589; PF00817; PF11799; PF16727; PF14377
In ASDno
Allosteric Predictionno (-0.549542435)
Ortholog in AnimalsAlpaca_ REV1 ( ortholog_one2one )
Dog_ AFF3 ( ortholog_one2one )
GuineaPig_ REV1 ( ortholog_one2one )
Macaque_ REV1 ( ortholog_one2one )
Mouse_ Rev1 ( ortholog_one2one )
Pig_ REV1 ( ortholog_one2one )
Rat_ Rev1 ( ortholog_one2one )
Rabbit_ REV1 ( ortholog_one2one )
OhnologsNA
ParalogsPOLI, ESCO1, POLH, ESCO2, POLK
TissueNA
Tissue SpecificityUbiquitous. {ECO:0000269|PubMed:10536157, ECO:0000269|PubMed:11278384, ECO:0000269|PubMed:11485998}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2EBW  (NMR  2LSI  (NMR  2LSK  (NMR  2LSY  (NMR  2N1G  (NMR  3GQC  (X-ray  2.50A  3VU7  (X-ray  2.80A  4BA9  (X-ray  2.73A  4EXT  (X-ray  1.90A  4GK0  (X-ray  2.70A  4GK5  (X-ray  3.21A  5VZM  (NMR  6ASR  (X-ray  2.36A  6AXD  (NMR  6WS0  (X-ray  2.24A  6WS5  (X-ray  2.47A 
DBSNP rs3087403  rs3087386  rs28382882  rs3087399  rs3087394  rs3087398  rs28382941  rs28382942  rs28382961  rs28382960  rs3087396  rs3087401  rs3087388  rs3087393  rs3087392  rs3087400 
Subcellular location [CC]Nucleus {ECO:0000305}.
Mouse PG classificationNA
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