| Gene Information | |
|---|---|
| Gene Name | NAT8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 227 |
| Protein Names | N-acetyltransferase 8 (EC 2.3.1.-) (Acetyltransferase 2) (ATase2) (Camello-like protein 1) (Cysteinyl-conjugate N-acetyltransferase) (CCNAT) (EC 2.3.1.80) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 18 ( ENSG00000144035 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9UHE5 |
| Gene Card | NAT8 |
| Uniprot ID | Q9UHE5 |
| Pfam | PF00583 |
| In ASD | no |
| Allosteric Prediction | no (-1.009415448) |
| Ortholog in Animals | Alpaca_ NAT8 ( ortholog_one2one ) Mouse_ Nat8f1 ( ortholog_many2many ) Mouse_ Nat8 ( ortholog_many2many ) Mouse_ Nat8f6 ( ortholog_many2many ) Mouse_ Nat8f7 ( ortholog_many2many ) Mouse_ Nat8f5 ( ortholog_many2many ) Mouse_ Nat8f3 ( ortholog_many2many ) Mouse_ Nat8f4 ( ortholog_many2many ) Mouse_ Nat8f2 ( ortholog_many2many ) Rat_ Nat8b ( ortholog_many2many ) Rat_ Nat8f2 ( ortholog_many2many ) Rat_ Nat8f1 ( ortholog_many2many ) Rat_ Nat8f5 ( ortholog_many2many ) Rat_ Nat8f4 ( ortholog_many2many ) Rat_ Nat8f3 ( ortholog_many2many ) Rat_ Nat8 ( ortholog_many2many ) |
| Ohnologs | NAT8L |
| Paralogs | NAT8B, NAT14, NAT8L |
| Tissue | kidney, cortex.of.kidney |
| Tissue Specificity | Preferentially expressed in liver and kidney. Also detected in brain (at protein level). {ECO:0000269|PubMed:22267734, ECO:0000269|PubMed:9852678}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.2(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs13424561 rs13538 |
| Subcellular location [CC] | Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane; Single-pass type II membrane protein. |
| Mouse PG classification | NA |
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