| Gene Information | |
|---|---|
| Gene Name | RETGC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1103 |
| Protein Names | Retinal guanylyl cyclase 1 (RETGC-1) (EC 4.6.1.2) (CG-E) (Guanylate cyclase 2D, retinal) (Rod outer segment membrane guanylate cyclase) (ROS-GC) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q02846 |
| Gene Card | GUCY2D |
| Uniprot ID | Q02846 |
| Pfam | PF01094; PF00211; PF07701; PF07714 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Retina. {ECO:0000269|PubMed:7912093}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.033333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs9905402 rs61749665 rs201414567 rs61749669 rs61749673 rs61749675 rs56280231 rs34596269 rs61749677 rs1451501407 rs565948960 rs746002871 rs61749755 rs61749756 rs770740012 rs61750162 rs35146471 rs34598902 rs781725943 rs34331388 rs61750168 rs8069344 rs375010731 rs61750171 rs28933695 rs61750172 rs61750173 rs61750173 rs1341592819 rs1598150539 rs61750176 rs1567961680 rs1598150793 rs1567961904 rs267606857 rs61750182 |
| Subcellular location [CC] | Photoreceptor outer segment membrane {ECO:0000269|PubMed:7912093}; Single-pass type I membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:30319355}; Single-pass type I membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |