| Gene Information | |
|---|---|
| Gene Name | THOC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1593 |
| Protein Names | THO complex subunit 2 (Tho2) (hTREX120) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000125676 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8NI27 |
| Gene Card | THOC2 |
| Uniprot ID | Q8NI27 |
| Pfam | PF11262; PF11732; PF16134 |
| In ASD | no |
| Allosteric Prediction | no (-0.72717879) |
| Ortholog in Animals | Alpaca_ THOC2 ( ortholog_one2one ) Dog_ THOC2 ( ortholog_one2one ) GuineaPig_ THOC2 ( ortholog_one2one ) Macaque_ THOC2 ( ortholog_one2one ) Mouse_ Thoc2 ( ortholog_one2many ) Mouse_ Thoc2l ( ortholog_one2many ) Pig_ THOC2 ( ortholog_one2one ) Rat_ Thoc2 ( ortholog_one2many ) Rat_ Thoc2l ( ortholog_one2many ) Rabbit_ THOC2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in the hippocampus and the cerebral cortex. {ECO:0000269|PubMed:26166480}. |
| Pharmacological Animal Models | 0.063623(Chimpanzee);0.028428(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7APK (EM 3.30A ) |
| DBSNP | rs797045019 rs797045018 rs797045021 rs797045020 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. Nucleus speckle {ECO:0000305}. |
| Mouse PG classification | NA |
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