| Gene Information | |
|---|---|
| Gene Name | M6PR |
| Organism | Homo sapiens (Human) |
| Gene Length | 277 |
| Protein Names | Cation-dependent mannose-6-phosphate receptor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46) |
| Target Name | mannose-6-phosphate receptor |
| Target Type | Successful target |
| Gene Age | 454 ( ENSG00000003056 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | P20645 |
| Gene Card | M6PR |
| Uniprot ID | P20645 |
| Pfam | PF02157 |
| In ASD | no |
| Allosteric Prediction | no (-0.212049841) |
| Ortholog in Animals | Alpaca_ M6PR ( ortholog_one2one ) Dog_ M6PR ( ortholog_one2one ) GuineaPig_ M6PR ( ortholog_one2one ) Macaque_ M6PR ( ortholog_one2one ) Mouse_ M6pr ( ortholog_one2one ) Pig_ M6PR ( ortholog_one2one ) Rat_ M6pr ( ortholog_one2many ) Rabbit_ M6PR ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1JUQ (X-ray 2.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Lysosome membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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