| Gene Information | |
|---|---|
| Gene Name | REPA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 270 |
| Protein Names | Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P15927 |
| Gene Card | RPA2 |
| Uniprot ID | P15927 |
| Pfam | PF08784 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002490(Rat);0.04(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1DPU (NMR - ) 1L1O (X-ray 2.80A ) 1QUQ (X-ray 2.50A ) 1Z1D (NMR - ) 2PI2 (X-ray 2.00A ) 2PQA (X-ray 2.50A ) 2Z6K (X-ray 3.00A ) 3KDF (X-ray 1.98A ) 4MQV (X-ray 1.95A ) 4OU0 (X-ray 1.40A ) |
| DBSNP | rs28988896 rs28988897 rs28904899 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:10982866, ECO:0000269|PubMed:12814551, ECO:0000269|PubMed:20154705, ECO:0000269|PubMed:21504906}. Nucleus, PML body {ECO:0000269|PubMed:12814551}. Note=Redistributes to discrete nuclear foci upon DNA damage in an ATR-dependent manner. {ECO:0000269|PubMed:12814551}. |
| Mouse PG classification | NA |
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