Gene Information
Gene NameREM2
OrganismHomo sapiens (Human)
Gene Length340
Protein NamesGTP-binding protein REM 2 (Rad and Gem-like GTP-binding protein 2)
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000139890 )
Evolutionary StageEukaryota
AlphaFoldDBQ8IYK8
Gene CardREM2
Uniprot IDQ8IYK8
PfamPF00071
In ASDno
Allosteric Predictionno (-1.797497338)
Ortholog in AnimalsAlpaca_ REM2 ( ortholog_one2one )
GuineaPig_ REM2 ( ortholog_one2one )
Macaque_ REM2 ( ortholog_one2one )
Mouse_ Rem2 ( ortholog_one2one )
Pig_ REM2 ( ortholog_one2one )
Rat_ Rem2 ( ortholog_one2one )
OhnologsREM1, RRAD, GEM
ParalogsRRAS, RHEB, KRAS, DIRAS1, RRAS2, RAP2B, HRAS, RERG, RASL12, RRAD, RIT1, DIRAS2, ERAS, NKIRAS1, RALB, RASD2, GEM, DIRAS3, MRAS, RAP2A, RASD1, REM1, NKIRAS2, RALA, RAP1A, RASL11B, RAP1B, RASL10A, RASL11A, RERGL, RIT2, RHEBL1, NRAS, RAP2C, RASL10B
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3CBQ  (X-ray  1.82A 
DBSNP rs8014119 
Subcellular location [CC]Cell membrane {ECO:0000250|UniProtKB:Q9WTY2}.
Mouse PG classificationNA
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