| Gene Information | |
|---|---|
| Gene Name | RELP |
| Organism | Homo sapiens (Human) |
| Gene Length | 158 |
| Protein Names | Regenerating islet-derived protein 4 (REG-4) (Gastrointestinal secretory protein) (REG-like protein) (Regenerating islet-derived protein IV) (Reg IV) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9BYZ8 |
| Gene Card | REG4 |
| Uniprot ID | Q9BYZ8 |
| Pfam | PF00059 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentially expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells. {ECO:0000269|PubMed:11311942, ECO:0000269|PubMed:12455032, ECO:0000269|PubMed:12819006}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2KV3 (NMR - ) |
| DBSNP | rs34996202 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:12819006}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |