Gene Information
Gene NameREG3G
OrganismHomo sapiens (Human)
Gene Length175
Protein NamesRegenerating islet-derived protein 3-gamma (REG-3-gamma) (Pancreatitis-associated protein 1B) (PAP-1B) (Pancreatitis-associated protein IB) (PAP IB) (Regenerating islet-derived protein III-gamma) (REG III) (Reg III-gamma) [Cleaved into: Regenerating islet-derived protein 3-gamma 16.5 kDa form; Regenerating islet-derived protein 3-gamma 15 kDa form]
Target NameNA
Target TypeNA
Gene Age680 ( ENSG00000143954 )
Evolutionary StageEumetazoa
AlphaFoldDBQ6UW15
Gene CardREG3G
Uniprot IDQ6UW15
PfamPF00059
In ASDno
Allosteric Predictionno (-1.026940638)
Ortholog in AnimalsAlpaca_ REG3G ( ortholog_one2one )
Dog_ REG3A ( ortholog_many2many )
Macaque_ REG3G ( ortholog_one2one )
OhnologsNA
ParalogsREG3A, CLEC19A, REG4, REG1B, REG1A
Tissuetestis, pancreas
Tissue SpecificityPredominantly expressed in pancreas, where it may be restricted to exocrine pancreas. Moderate expression levels in testis and weak in heart, kidney and placenta. {ECO:0000269|PubMed:15556304, ECO:0000269|PubMed:15777617}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Secreted. Cytoplasm {ECO:0000250}.
Mouse PG classificationNA
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