| Gene Information | |
|---|---|
| Gene Name | RECK |
| Organism | Homo sapiens (Human) |
| Gene Length | 971 |
| Protein Names | Reversion-inducing cysteine-rich protein with Kazal motifs (hRECK) (Suppressor of tumorigenicity 15 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000122707 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O95980 |
| Gene Card | RECK |
| Uniprot ID | O95980 |
| Pfam | PF07648 |
| In ASD | no |
| Allosteric Prediction | no (-0.513670749) |
| Ortholog in Animals | Alpaca_ RECK ( ortholog_one2one ) Dog_ RECK ( ortholog_one2one ) GuineaPig_ RECK ( ortholog_one2one ) Macaque_ RECK ( ortholog_one2one ) Mouse_ Reck ( ortholog_one2one ) Pig_ RECK ( ortholog_one2one ) Rat_ Reck ( ortholog_one2one ) Rabbit_ RECK ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in various tissues and untransformed cells (PubMed:9789069). It is undetectable in tumor-derived cell lines and oncogenically transformed cells (PubMed:9789069). {ECO:0000269|PubMed:9789069}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs16932912 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:30026314, ECO:0000269|PubMed:9789069}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:9789069}. |
| Mouse PG classification | NA |
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