| Gene Information | |
|---|---|
| Gene Name | RDX |
| Organism | Homo sapiens (Human) |
| Gene Length | 583 |
| Protein Names | Radixin |
| Target Name | radixin |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000137710 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | P35241 |
| Gene Card | RDX |
| Uniprot ID | P35241 |
| Pfam | PF00769; PF20492; PF09380; PF00373; PF09379 |
| In ASD | no |
| Allosteric Prediction | yes (0.861740184) |
| Ortholog in Animals | Alpaca_ RDX ( ortholog_one2one ) Dog_ RDX ( ortholog_one2one ) GuineaPig_ RDX ( ortholog_one2one ) Macaque_ RDX ( ortholog_one2one ) Mouse_ Rdx ( ortholog_one2one ) Pig_ RDX ( ortholog_one2one ) Rat_ Rdx ( ortholog_one2one ) Rabbit_ RDX ( ortholog_one2one ) |
| Ohnologs | MSN, EZR |
| Paralogs | MSN, EZR, FRMD4B, NF2, ERMN, FRMD4A |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17854427 rs34471100 rs121918379 |
| Subcellular location [CC] | Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cleavage furrow. Cell projection, microvillus {ECO:0000250|UniProtKB:P26043}. Note=Highly concentrated in the undercoat of the cell-to-cell adherens junction and the cleavage furrow in the interphase and mitotic phase, respectively. |
| Mouse PG classification | HPG |
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