| Gene Information | |
|---|---|
| Gene Name | FGF12 |
| Organism | Homo sapiens (Human) |
| Gene Length | 243 |
| Protein Names | Fibroblast growth factor 12 (FGF-12) (Fibroblast growth factor homologous factor 1) (FHF-1) (Myocyte-activating factor) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000114279 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P61328 |
| Gene Card | FGF12 |
| Uniprot ID | P61328 |
| Pfam | PF00167 |
| In ASD | no |
| Allosteric Prediction | no (-0.136261327) |
| Ortholog in Animals | Alpaca_ FGF12 ( ortholog_one2one ) Dog_ FGF12 ( ortholog_one2one ) GuineaPig_ FGF12 ( ortholog_one2one ) Macaque_ FGF12 ( ortholog_one2one ) Mouse_ Fgf12 ( ortholog_one2one ) Pig_ FGF12 ( ortholog_one2one ) Rat_ Fgf12 ( ortholog_one2one ) Rabbit_ FGF12 ( ortholog_one2one ) |
| Ohnologs | FGF14, FGF6, FGF1, FGF13, FGF11, FGF3, FGF16 |
| Paralogs | FGF1, FGF16, FGF14, FGF21, FGF3, FGF10, FGF5, FGF9, FGF7, FGF22, FGF6, FGF23, FGF19, FGF17, FGF13, FGF8, FGF18, FGF11, FGF20, FGF2, FGF4 |
| Tissue | adrenal.gland, cerebral.cortex, heart, brain, spleen |
| Tissue Specificity | Brain, eye and testis; highly expressed in embryonic retina, olfactory epithelium, olfactory bulb, and in a segmental pattern of the body wall; in adult olfactory bulb, less in cerebellum, deep cerebellar nuclei, cortex and multiple midbrain structures. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.044444(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1Q1U (X-ray 1.70A ) 4JQ0 (X-ray 3.84A ) |
| DBSNP | rs886039903 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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