| Gene Information | |
|---|---|
| Gene Name | RD |
| Organism | Homo sapiens (Human) |
| Gene Length | 380 |
| Protein Names | Negative elongation factor E (NELF-E) (RNA-binding protein RD) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P18615 |
| Gene Card | NELFE |
| Uniprot ID | P18615 |
| Pfam | PF00076 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed in heart, brain, lung, placenta, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:12612062}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.025442(Rat);0.058065(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1X5P (NMR - ) 2BZ2 (NMR - ) 2JX2 (NMR - ) 5OOB (X-ray 2.79A ) 6GML (EM 3.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:14701750}. Chromosome {ECO:0000269|PubMed:14701750}. Note=Localizes to chromatin (PubMed:14701750). Phosphorylation by the P-TEFb complex promotes its release from chromatin (PubMed:14701750). {ECO:0000269|PubMed:14701750}. |
| Mouse PG classification | NA |
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