Gene Information
Gene NameRCE1
OrganismHomo sapiens (Human)
Gene Length329
Protein NamesCAAX prenyl protease 2 (EC 3.4.-.-) (Farnesylated proteins-converting enzyme 2) (FACE-2) (Prenyl protein-specific endoprotease 2) (RCE1 homolog) (hRCE1)
Target Nameras converting caax endopeptidase 1
Target TypeLiterature-reported target
Gene Age680 ( ENSG00000173653 )
Evolutionary StageEukaryota
AlphaFoldDBQ9Y256
Gene CardRCE1
Uniprot IDQ9Y256
PfamPF02517
In ASDno
Allosteric Predictionno (-0.70523444)
Ortholog in AnimalsAlpaca_ RCE1 ( ortholog_one2one )
Dog_ RCE1 ( ortholog_one2one )
GuineaPig_ RCE1 ( ortholog_one2one )
Macaque_ RCE1 ( ortholog_one2one )
Mouse_ Rce1 ( ortholog_one2one )
Pig_ RCE1 ( ortholog_one2one )
Rat_ Rce1 ( ortholog_one2one )
Rabbit_ RCE1 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityUbiquitous. {ECO:0000269|PubMed:10085068}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Endoplasmic reticulum membrane {ECO:0000269|PubMed:19188362};
Multi-pass membrane protein {ECO:0000269|PubMed:19188362}.
Mouse PG classificationNA
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