| Gene Information | |
|---|---|
| Gene Name | RCC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 421 |
| Protein Names | Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000180198 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P18754 |
| Gene Card | RCC1 |
| Uniprot ID | P18754 |
| Pfam | PF00415 |
| In ASD | no |
| Allosteric Prediction | yes (0.096073786) |
| Ortholog in Animals | Alpaca_ RCC1 ( ortholog_one2one ) Dog_ RCC1 ( ortholog_one2one ) GuineaPig_ RCC1 ( ortholog_one2one ) Macaque_ RCC1 ( ortholog_one2one ) Mouse_ Rcc1 ( ortholog_one2one ) Pig_ RCC1 ( ortholog_one2one ) Rat_ Rcc1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SERGEF, RCC2, RCBTB2, RCBTB1, RCC1L, RPGR, RCCD1, HERC1, ALS2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.089583(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1A12 (X-ray 1.70A ) 1I2M (X-ray 1.76A ) 5E1B (X-ray 1.65A ) 5E1D (X-ray 1.45A ) 5E1M (X-ray 1.75A ) 5E1O (X-ray 2.00A ) 5E2A (X-ray 1.75A ) 5E2B (X-ray 1.95A ) 5TBK (X-ray 3.45A ) 6DUB (X-ray 1.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:12194828, ECO:0000269|PubMed:16820410, ECO:0000269|PubMed:17435751, ECO:0000269|PubMed:2236072}. Chromosome {ECO:0000269|PubMed:12194828, ECO:0000269|PubMed:17435751, ECO:0000269|PubMed:18762580, ECO:0000269|PubMed:20668449}. Cytoplasm {ECO:0000269|PubMed:12194828, ECO:0000269|PubMed:17435751, ECO:0000269|PubMed:20668449}. Note=Predominantly nuclear in interphase cells (PubMed:12194828). Binds to mitotic chromosomes (PubMed:12194828, PubMed:17435751, PubMed:20668449). {ECO:0000269|PubMed:12194828, ECO:0000269|PubMed:17435751, ECO:0000269|PubMed:20668449}. |
| Mouse PG classification | NA |
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