| Gene Information | |
|---|---|
| Gene Name | RBSN |
| Organism | Homo sapiens (Human) |
| Gene Length | 784 |
| Protein Names | Rabenosyn-5 (110 kDa protein) (FYVE finger-containing Rab5 effector protein rabenosyn-5) (RAB effector RBSN) (Zinc finger FYVE domain-containing protein 20) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000131381 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9H1K0 |
| Gene Card | RBSN |
| Uniprot ID | Q9H1K0 |
| Pfam | PF01363; PF11464 |
| In ASD | no |
| Allosteric Prediction | no (-0.903194112) |
| Ortholog in Animals | Alpaca_ RBSN ( ortholog_one2one ) Dog_ RBSN ( ortholog_one2one ) GuineaPig_ RBSN ( ortholog_one2one ) Macaque_ RBSN ( ortholog_one2one ) Mouse_ Rbsn ( ortholog_one2one ) Pig_ RBSN ( ortholog_one2one ) Rat_ Rbsn ( ortholog_one2one ) Rabbit_ RBSN ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1YZM (X-ray 1.50A ) 1Z0J (X-ray 1.32A ) 1Z0K (X-ray 1.92A ) |
| DBSNP | rs144008665 rs9868848 rs9851219 rs9830744 |
| Subcellular location [CC] | Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane {ECO:0000269|PubMed:22308388}; Lipid-anchor. Note=Enriched in endosomes that are in close proximity to clathrin-enriched regions at the cell surface. {ECO:0000269|PubMed:22308388}. |
| Mouse PG classification | NA |
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