| Gene Information | |
|---|---|
| Gene Name | RBP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 135 |
| Protein Names | Retinol-binding protein 1 (Cellular retinol-binding protein) (CRBP) (Cellular retinol-binding protein I) (CRBP-I) |
| Target Name | retinol-binding protein 1 |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000114115 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P09455 |
| Gene Card | RBP1 |
| Uniprot ID | P09455 |
| Pfam | PF00061 |
| In ASD | no |
| Allosteric Prediction | no (-0.166112168) |
| Ortholog in Animals | Alpaca_ RBP1 ( ortholog_one2one ) GuineaPig_ RBP1 ( ortholog_one2one ) Mouse_ Rbp1 ( ortholog_one2one ) Pig_ RBP1 ( ortholog_one2one ) Rat_ Rbp1 ( ortholog_one2one ) |
| Ohnologs | RBP5, RBP7 |
| Paralogs | CRABP1, FABP9, FABP5, FABP12, FABP4, PMP2, RBP2, RBP5, RBP7, FABP3, FABP2, FABP6, FABP7, FABP1, CRABP2 |
| Tissue | NA |
| Tissue Specificity | Detected in nearly all the tissues with higher expression in adult ovary, pancreas, pituitary gland and adrenal gland, and fetal liver. {ECO:0000269|PubMed:11274389}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5H8T (X-ray 1.21A ) 5H9A (X-ray 1.38A ) 5HA1 (X-ray 1.35A ) 5HBS (X-ray 0.89A ) 5LJB (X-ray 1.26A ) 5LJC (X-ray 1.43A ) 5LJD (X-ray 1.61A ) 5LJE (X-ray 1.40A ) 5LJG (X-ray 1.15A ) 5LJH (X-ray 1.52A ) 5LJK (X-ray 1.70A ) 6E5L (X-ray 1.17A ) 6E5T (X-ray 1.55A ) 6E6M (X-ray 1.55A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000305|PubMed:22665496}. Lipid droplet {ECO:0000269|PubMed:15632377}. |
| Mouse PG classification | NA |
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