Gene Information
Gene NameRBM8A
OrganismHomo sapiens (Human)
Gene Length174
Protein NamesRNA-binding protein 8A (Binder of OVCA1-1) (BOV-1) (RNA-binding motif protein 8A) (RNA-binding protein Y14) (Ribonucleoprotein RBM8A)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000265241 )
Evolutionary StageEukaryota
AlphaFoldDBQ9Y5S9
Gene CardRBM8A
Uniprot IDQ9Y5S9
PfamPF00076
In ASDno
Allosteric Predictionno (-0.75561263)
Ortholog in AnimalsAlpaca_ RBM8A ( ortholog_one2one )
Dog_ RBM8A ( ortholog_one2one )
GuineaPig_ RBM8A ( ortholog_one2one )
Macaque_ RBM8A ( ortholog_one2one )
Mouse_ Rbm8a ( ortholog_one2many )
Mouse_ Rbm8a2 ( ortholog_one2many )
Pig_ RBM8A ( ortholog_one2one )
Rat_ Rbm8a ( ortholog_one2one )
Rabbit_ RBM8A ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityUbiquitous.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.002479(Rat);0.156298(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1P27  (X-ray  2.00A  )  2HYI  (X-ray  2.30A  )  2J0Q  (X-ray  3.20A  )  2J0S  (X-ray  2.21A  )  2XB2  (X-ray  3.40A  )  3EX7  (X-ray  2.30A  )  5XJC  (EM  3.60A  )  5YZG  (EM  4.10A  )  6ICZ  (EM  3.00A  )  6QDV  (EM  3.30A  )  7A5P  (EM  5.00A  )  7W59  (EM  3.60A  )  7W5A  (EM  3.60A  )  7W5B  (EM  4.30A  ) 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:11030346, ECO:0000269|PubMed:19324961, ECO:0000269|PubMed:28502770, ECO:0000269|PubMed:29301961}. Nucleus speckle {ECO:0000269|PubMed:11030346, ECO:0000269|PubMed:19324961}. Cytoplasm {ECO:0000269|PubMed:11030346, ECO:0000269|PubMed:19324961}. Note=Nucleocytoplasmic shuttling protein (PubMed:11030346). Travels to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA. Colocalizes with the core EJC, ALYREF/THOC4, NXF1 and UAP56 in the nucleus and nuclear speckles (PubMed:19324961). {ECO:0000269|PubMed:11030346, ECO:0000269|PubMed:19324961}.
Mouse PG classificationNA
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