| Gene Information | |
|---|---|
| Gene Name | RBM5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 815 |
| Protein Names | RNA-binding protein 5 (Protein G15) (Putative tumor suppressor LUCA15) (RNA-binding motif protein 5) (Renal carcinoma antigen NY-REN-9) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000003756 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P52756 |
| Gene Card | RBM5 |
| Uniprot ID | P52756 |
| Pfam | PF01585; PF17780; PF00076; PF00641 |
| In ASD | no |
| Allosteric Prediction | no (-0.553251296) |
| Ortholog in Animals | Alpaca_ RBM5 ( ortholog_one2one ) Dog_ RBM5 ( ortholog_one2one ) GuineaPig_ RBM5 ( ortholog_one2one ) Macaque_ RBM5 ( ortholog_one2one ) Mouse_ Rbm5 ( ortholog_one2one ) Pig_ RBM5 ( ortholog_one2one ) Rat_ Rbm5 ( ortholog_one2one ) Rabbit_ RBM5 ( ortholog_one2one ) |
| Ohnologs | RBM10 |
| Paralogs | RBM6, RBM10 |
| Tissue | NA |
| Tissue Specificity | Isoform 5 is widely expressed in normal tissues and is expressed at increased levels in T-leukemic cell lines. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001407(Rat);0.018182(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2LK0 (NMR - ) 2LK1 (NMR - ) 2LKZ (NMR - ) 5MF9 (NMR - ) 5MFY (NMR - ) 7PCV (X-ray 2.42A ) |
| DBSNP | rs56783610 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:18851835}. |
| Mouse PG classification | NA |
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