Gene Information
Gene NameRBM22
OrganismHomo sapiens (Human)
Gene Length420
Protein NamesPre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22) (Zinc finger CCCH domain-containing protein 16)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000086589 )
Evolutionary StageEukaryota
AlphaFoldDBQ9NW64
Gene CardRBM22
Uniprot IDQ9NW64
PfamPF00076
In ASDno
Allosteric Predictionno (-0.77032412)
Ortholog in AnimalsAlpaca_ RBM22 ( ortholog_one2one )
Dog_ RBM22 ( ortholog_one2one )
GuineaPig_ RBM22 ( ortholog_one2one )
Macaque_ RBM22 ( ortholog_one2one )
Mouse_ Rbm22 ( ortholog_one2one )
Pig_ RBM22 ( ortholog_one2one )
Rat_ Rbm22 ( ortholog_one2one )
Rabbit_ RBM22 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.197783(Rat);0.153410(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2YTC  (NMR  -  )  5MQF  (EM  5.90A  )  5XJC  (EM  3.60A  )  5YZG  (EM  4.10A  )  5Z56  (EM  5.10A  )  5Z57  (EM  6.50A  )  6FF4  (EM  16.00A  )  6FF7  (EM  4.50A  )  6ICZ  (EM  3.00A  )  6ID0  (EM  2.90A  )  6ID1  (EM  2.86A  )  6QDV  (EM  3.30A  )  6ZYM  (EM  3.40A  )  7A5P  (EM  5.00A  )  7AAV  (EM  4.20A  )  7ABG  (EM  7.80A  )  7ABI  (EM  8.00A  )  7W59  (EM  3.60A  )  7W5A  (EM  3.60A  )  7W5B  (EM  4.30A  ) 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:17045351, ECO:0000269|PubMed:21122810, ECO:0000269|PubMed:28076346, ECO:0000269|PubMed:28502770, ECO:0000269|PubMed:29301961, ECO:0000269|PubMed:29360106, ECO:0000269|PubMed:29361316, ECO:0000269|PubMed:30705154}. Cytoplasm {ECO:0000269|PubMed:21122810}. Note=Nearly exclusively nuclear. Translocated from the nucleus to the cytoplasm after heat shock cell treatment. May be shuttling between the nucleus and the cytosol. {ECO:0000269|PubMed:21122810}.
Mouse PG classificationNA
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