| Gene Information | |
|---|---|
| Gene Name | AREG |
| Organism | Homo sapiens (Human) |
| Gene Length | 252 |
| Protein Names | Amphiregulin (AR) (Colorectum cell-derived growth factor) (CRDGF) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000109321 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P15514 |
| Gene Card | AREG |
| Uniprot ID | P15514 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | yes (0.251330422) |
| Ortholog in Animals | Alpaca_ AREG ( ortholog_one2one ) Dog_ AREG ( ortholog_one2one ) GuineaPig_ AREG ( ortholog_one2one ) Macaque_ AREG ( ortholog_one2one ) Mouse_ Areg ( ortholog_one2one ) Pig_ AREG ( ortholog_one2one ) Rat_ Areg ( ortholog_one2one ) Rabbit_ AREG ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | EREG, BTC, EPGN, TGFA, HBEGF |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.05(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2RNL (NMR - ) |
| DBSNP | rs373527160 rs28364979 |
| Subcellular location [CC] | Membrane; Single-pass membrane protein. |
| Mouse PG classification | NA |
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