| Gene Information | |
|---|---|
| Gene Name | RBL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1139 |
| Protein Names | Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (p130) (Retinoblastoma-related protein 2) (RBR-2) (pRb2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000103479 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q08999 |
| Gene Card | RBL2 |
| Uniprot ID | Q08999 |
| Pfam | PF11934; PF01858; PF01857 |
| In ASD | no |
| Allosteric Prediction | yes (0.307665871) |
| Ortholog in Animals | Alpaca_ RBL2 ( ortholog_one2one ) Dog_ RBL2 ( ortholog_one2one ) GuineaPig_ RBL2 ( ortholog_one2one ) Macaque_ RBL2 ( ortholog_one2one ) Mouse_ Rbl2 ( ortholog_one2one ) Pig_ RBL2 ( ortholog_one2one ) Rat_ Rbl2 ( ortholog_one2one ) Rabbit_ RBL2 ( ortholog_one2one ) |
| Ohnologs | RBL1 |
| Paralogs | RBL1, RB1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001847(Rat);0.042105(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4XI9 (X-ray 3.10A ) 5C1D (X-ray 2.05A ) |
| DBSNP | rs17800727 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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