| Gene Information | |
|---|---|
| Gene Name | RAX |
| Organism | Homo sapiens (Human) |
| Gene Length | 313 |
| Protein Names | Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PKR-associated protein X) (PKR-associating protein X) (Protein activator of the interferon-induced protein kinase) (Protein kinase, interferon-inducible double-stranded RNA-dependent activator) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000134438 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O75569 |
| Gene Card | PRKRA |
| Uniprot ID | O75569 |
| Pfam | PF00035 |
| In ASD | no |
| Allosteric Prediction | no (-1.45382174) |
| Ortholog in Animals | Alpaca_ RAX ( ortholog_one2one ) Dog_ RAX ( ortholog_one2one ) GuineaPig_ RAX ( ortholog_one2one ) Macaque_ RAX ( ortholog_one2one ) Mouse_ Rax ( ortholog_one2one ) Pig_ RAX ( ortholog_one2one ) Rat_ Rax ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ARGFX, PAX7, PAX3, ALX4, PAX2, UNCX, RAX2, PAX8, DMBX1, DPRX, PAX5, ISX, ALX3, RHOXF2B, RHOXF2, GSC2, SEBOX, DRGX, ARX, RHOXF1, PITX3, PRRX1, SHOX, SHOX2, PRRX2, OTX2, PAX4, EVX1, PAX1, PITX2, PHOX2A, CRX, PHOX2B, EVX2, ALX1, VSX2, MIXL1, DUXA, PAX6, OTP, HESX1, NOBOX, PROP1, PAX9, GSC, ESX1, DUXB, DUX4, PITX1, OTX1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002419(Rat);0.042857(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2DIX (NMR - ) |
| DBSNP | rs121434410 |
| Subcellular location [CC] | Cytoplasm, perinuclear region. Cytoplasm. |
| Mouse PG classification | HPG |
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