| Gene Information | |
|---|---|
| Gene Name | POLD4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 107 |
| Protein Names | DNA polymerase delta subunit 4 (DNA polymerase delta subunit p12) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000175482 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9HCU8 |
| Gene Card | POLD4 |
| Uniprot ID | Q9HCU8 |
| Pfam | PF04081 |
| In ASD | no |
| Allosteric Prediction | no (-0.528211438) |
| Ortholog in Animals | Alpaca_ POLD4 ( ortholog_one2one ) Dog_ CLCF1 ( ortholog_one2many ) GuineaPig_ POLD4 ( ortholog_one2one ) Macaque_ POLD4 ( ortholog_one2one ) Mouse_ Pold4 ( ortholog_one2one ) Pig_ POLD4 ( ortholog_one2one ) Rat_ Pold4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.743407(Rat);0.151786(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6HVO (X-ray 2.10A ) 6S1M (EM 4.27A ) 6S1N (EM 4.86A ) 6S1O (EM 8.10A ) 6TNY (EM 3.08A ) 6TNZ (EM 4.05A ) |
| DBSNP | rs28364240 rs34136263 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:22801543}. Note=Partially recruited to DNA damage sites within 2 hours following UV irradiation, before degradation. {ECO:0000269|PubMed:22801543}. |
| Mouse PG classification | NA |
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