| Gene Information | |
|---|---|
| Gene Name | RASAL3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1011 |
| Protein Names | RAS protein activator like-3 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000105122 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q86YV0 |
| Gene Card | RASAL3 |
| Uniprot ID | Q86YV0 |
| Pfam | PF00616 |
| In ASD | no |
| Allosteric Prediction | no (-0.890972849) |
| Ortholog in Animals | Alpaca_ RASAL3 ( ortholog_one2one ) Dog_ RASAL3 ( ortholog_one2one ) GuineaPig_ RASAL3 ( ortholog_one2one ) Macaque_ RASAL3 ( ortholog_one2one ) Mouse_ Rasal3 ( ortholog_one2one ) Pig_ RASAL3 ( ortholog_one2one ) Rat_ Rasal3 ( ortholog_one2one ) |
| Ohnologs | RASAL2, DAB2IP, SYNGAP1 |
| Paralogs | NF1, SYNGAP1, DAB2IP, RASAL1, RASA3, RASA1, RASA2, RASA4, RASA4B, RASAL2 |
| Tissue | appendix, lymph.node, spleen, submandibular.gland, whole.blood |
| Tissue Specificity | Predominantly expressed in cells of hematopoietic lineages. {ECO:0000269|PubMed:25652366}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs58123634 rs56209154 rs57208996 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:25652366}. Cytoplasm, cell cortex {ECO:0000269|PubMed:25652366}. |
| Mouse PG classification | NA |
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