| Gene Information | |
|---|---|
| Gene Name | RASAL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 804 |
| Protein Names | RasGAP-activating-like protein 1 (RAS protein activator like 1) (Ras GTPase-activating-like protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000111344 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O95294 |
| Gene Card | RASAL1 |
| Uniprot ID | O95294 |
| Pfam | PF00779; PF00168; PF00169; PF00616 |
| In ASD | no |
| Allosteric Prediction | no (-0.258047708) |
| Ortholog in Animals | Alpaca_ RASAL1 ( ortholog_one2one ) Dog_ RASAL1 ( ortholog_one2one ) GuineaPig_ RASAL1 ( ortholog_one2one ) Macaque_ RASAL1 ( ortholog_one2one ) Mouse_ Rasal1 ( ortholog_one2one ) Pig_ RASAL1 ( ortholog_one2one ) Rat_ Rasal1 ( ortholog_one2one ) Rabbit_ RASAL1 ( ortholog_one2one ) |
| Ohnologs | RASA4, RASA4B, POLR2J4 |
| Paralogs | NF1, SYNGAP1, DAB2IP, RASA3, RASA1, RASA2, RASA4, RASA4B, RASAL2, RASAL3 |
| Tissue | adrenal.gland |
| Tissue Specificity | Highly expressed in thyroid and adrenal medulla, lower expression in brain, spinal cord and trachea (PubMed:9751798). Expressed in melanocytes (PubMed:23999003). {ECO:0000269|PubMed:23999003, ECO:0000269|PubMed:9751798}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7960087 rs34598602 rs1284879 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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