| Gene Information | |
|---|---|
| Gene Name | MIR10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 597 |
| Protein Names | Leukocyte immunoglobulin-like receptor subfamily B member 2 (LIR-2) (Leukocyte immunoglobulin-like receptor 2) (CD85 antigen-like family member D) (Immunoglobulin-like transcript 4) (ILT-4) (Monocyte/macrophage immunoglobulin-like receptor 10) (MIR-10) (CD antigen CD85d) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8N423 |
| Gene Card | LILRB2 |
| Uniprot ID | Q8N423 |
| Pfam | PF13895 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in monocytes and at lower levels in myeloid and plasmacytoid dendritic cells. Expressed in tolerogenic IL10-producing dendritic cells (PubMed:20448110). Expressed in myeloid-derived suppressor cells during pregnancy (PubMed:27859042). Detected at low levels in natural killer (NK) cells. Expressed in B cells. {ECO:0000269|PubMed:20448110, ECO:0000269|PubMed:27859042, ECO:0000269|PubMed:9548455, ECO:0000269|PubMed:9842885}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2DYP (X-ray 2.50A ) 2GW5 (X-ray 1.80A ) 4LLA (X-ray 2.50A ) 6AED (X-ray 3.80A ) 6BCS (X-ray 2.10A ) |
| DBSNP | rs383369 rs373032 rs386056 rs7247538 rs7247451 rs1128646 rs7247055 rs7246737 rs7247025 rs4993133 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:20448110}; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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