| Gene Information | |
|---|---|
| Gene Name | RARG |
| Organism | Homo sapiens (Human) |
| Gene Length | 454 |
| Protein Names | Retinoic acid receptor gamma (RAR-gamma) (Nuclear receptor subfamily 1 group B member 3) |
| Target Name | retinoic acid receptor gamma |
| Target Type | Successful target |
| Gene Age | 810 ( ENSG00000172819 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P13631 |
| Gene Card | RARG |
| Uniprot ID | P13631 |
| Pfam | PF00104; PF00105 |
| In ASD | no |
| Allosteric Prediction | yes (0.596605335) |
| Ortholog in Animals | Alpaca_ RARG ( ortholog_one2one ) Dog_ RARG ( ortholog_one2one ) GuineaPig_ RARG ( ortholog_one2one ) Macaque_ RARG ( ortholog_one2one ) Mouse_ Rarg ( ortholog_one2one ) Pig_ RARG ( ortholog_one2one ) Rat_ Rarg ( ortholog_one2one ) |
| Ohnologs | RARA, RARB, PPARG |
| Paralogs | NR1H4, VDR, NR1D2, RARA, PPARD, NR1H2, RORC, THRB, NR1D1, NR1H3, NR1I2, PPARG, NR1I3, RARB, RORB, PPARA, RORA, THRA |
| Tissue | NA |
| Tissue Specificity | Expressed in aortic endothelial cells (at protein level). {ECO:0000269|PubMed:28167758}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1EXA (X-ray 1.59A ) 1EXX (X-ray 1.67A ) 1FCX (X-ray 1.47A ) 1FCY (X-ray 1.30A ) 1FCZ (X-ray 1.38A ) 1FD0 (X-ray 1.38A ) 2LBD (X-ray 2.06A ) 3LBD (X-ray 2.40A ) 4LBD (X-ray 2.50A ) 5M24 (X-ray 1.69A ) 6FX0 (X-ray 1.90A ) |
| DBSNP | rs2229774 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:28167758}. Cytoplasm {ECO:0000269|PubMed:28167758}. |
| Mouse PG classification | NA |
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