| Gene Information | |
|---|---|
| Gene Name | RAP3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 366 |
| Protein Names | Apolipoprotein A-V (Apo-AV) (ApoA-V) (Apolipoprotein A5) (Regeneration-associated protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q6Q788 |
| Gene Card | APOA5 |
| Uniprot ID | Q6Q788 |
| Pfam | PF01442 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Liver and plasma. {ECO:0000269|PubMed:11577099, ECO:0000269|PubMed:11588264, ECO:0000269|PubMed:15528295}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3135506 rs34282181 rs3135507 rs2075291 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:12810715}. Early endosome {ECO:0000269|PubMed:18603531}. Late endosome {ECO:0000269|PubMed:18603531}. Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:18603531}. Note=In the presence of SORL1, internalized to early endosomes, sorted in a retrograde fashion to late endosomes, from which a portion is sent to lysosomes and degradation, another portion is sorted to the trans-Golgi network. {ECO:0000269|PubMed:18603531}. |
| Mouse PG classification | NA |
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