| Gene Information | |
|---|---|
| Gene Name | RAP2B |
| Organism | Homo sapiens (Human) |
| Gene Length | 183 |
| Protein Names | Ras-related protein Rap-2b (EC 3.6.5.2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000181467 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P61225 |
| Gene Card | RAP2B |
| Uniprot ID | P61225 |
| Pfam | PF00071 |
| In ASD | no |
| Allosteric Prediction | yes (0.012392069) |
| Ortholog in Animals | Alpaca_ RAP2B ( ortholog_one2one ) Dog_ RAP2B ( ortholog_one2one ) GuineaPig_ RAP2B ( ortholog_one2one ) Macaque_ RAP2B ( ortholog_one2one ) Mouse_ Rap2b ( ortholog_one2one ) Pig_ RAP2B ( ortholog_one2one ) Rat_ Rap2b ( ortholog_one2one ) Rabbit_ RAP2B ( ortholog_one2one ) |
| Ohnologs | RAP2C, RAP2A |
| Paralogs | RRAS, RHEB, KRAS, DIRAS1, RRAS2, HRAS, RERG, RASL12, RRAD, RIT1, DIRAS2, ERAS, NKIRAS1, RALB, RASD2, GEM, DIRAS3, MRAS, RAP2A, RASD1, REM1, NKIRAS2, RALA, RAP1A, RASL11B, RAP1B, RASL10A, RASL11A, REM2, RERGL, RIT2, RHEBL1, NRAS, RAP2C, RASL10B |
| Tissue | NA |
| Tissue Specificity | Expressed in red blood cells (at protein level). {ECO:0000269|PubMed:16540189}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1N4P (X-ray 2.65A ) 1N4Q (X-ray 2.40A ) 1N4R (X-ray 2.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | Recycling endosome membrane {ECO:0000269|PubMed:16540189}; Lipid-anchor {ECO:0000269|PubMed:16540189}; Cytoplasmic side {ECO:0000269|PubMed:16540189}. Note=Associated with red blood cells-released vesicles. |
| Mouse PG classification | NA |
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