| Gene Information | |
|---|---|
| Gene Name | PRLHR |
| Organism | Homo sapiens (Human) |
| Gene Length | 370 |
| Protein Names | Prolactin-releasing peptide receptor (PrRP receptor) (PrRPR) (G-protein coupled receptor 10) (hGR3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000119973 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P49683 |
| Gene Card | PRLHR |
| Uniprot ID | P49683 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | no (-0.067517459) |
| Ortholog in Animals | Alpaca_ PRLHR ( ortholog_one2one ) Dog_ PRLHR ( ortholog_one2one ) GuineaPig_ PRLHR ( ortholog_one2one ) Macaque_ PRLHR ( ortholog_one2one ) Mouse_ Prlhr ( ortholog_one2one ) Pig_ PRLHR ( ortholog_one2one ) Rat_ Prlhr ( ortholog_one2one ) Rabbit_ PRLHR ( ortholog_one2one ) |
| Ohnologs | NPY2R |
| Paralogs | TACR2, OR9A2, NPY1R, MTNR1B, OR11H6, OR11H7, OR11H4, OR9A1P, OR9G1, NPY2R, MTNR1A, GPR50, GPR75, OR11G2, MCHR2, MCHR1, GPR19, OR11A1, TACR1, TACR3, OR11H2, OR11H12, OR11H1, GPR83, PROKR2, PROKR1, GPR88, OR51F1, OR10X1, NPY5R, OR9A4, NPY4R2, NPY4R |
| Tissue | NA |
| Tissue Specificity | Only detected in the pituitary gland and in all cell types of pituitary adenomas. {ECO:0000269|PubMed:10498338, ECO:0000269|PubMed:11923475}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1613448 rs8192523 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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