| Gene Information | |
|---|---|
| Gene Name | RANK |
| Organism | Homo sapiens (Human) |
| Gene Length | 616 |
| Protein Names | Tumor necrosis factor receptor superfamily member 11A (Osteoclast differentiation factor receptor) (ODFR) (Receptor activator of NF-KB) (CD antigen CD265) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9Y6Q6 |
| Gene Card | TNFRSF11A |
| Uniprot ID | Q9Y6Q6 |
| Pfam | PF18278; PF00020 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous expression with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001990(Rat);0.114286(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1LB5 (X-ray 2.40A ) |
| DBSNP | rs121908659 rs121908657 rs35211496 rs121908655 rs121908656 rs1805034 rs121908658 |
| Subcellular location [CC] | [Isoform 1]: Cell membrane {ECO:0000269|PubMed:23664977}; Single-pass type I membrane protein {ECO:0000269|PubMed:23664977}.; [Isoform RANK-e5a]: Cell membrane {ECO:0000269|PubMed:23664977}; Single-pass type I membrane protein {ECO:0000269|PubMed:23664977}. |
| Mouse PG classification | NA |
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