| Gene Information | |
|---|---|
| Gene Name | BCAN |
| Organism | Homo sapiens (Human) |
| Gene Length | 911 |
| Protein Names | Brevican core protein (Brain-enriched hyaluronan-binding protein) (BEHAB) (Chondroitin sulfate proteoglycan 7) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000132692 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96GW7 |
| Gene Card | BCAN |
| Uniprot ID | Q96GW7 |
| Pfam | PF00008; PF00059; PF00084; PF07686; PF00193 |
| In ASD | no |
| Allosteric Prediction | no (-0.497736539) |
| Ortholog in Animals | Alpaca_ BCAN ( ortholog_one2one ) Dog_ BCAN ( ortholog_one2one ) GuineaPig_ BCAN ( ortholog_one2one ) Macaque_ BCAN ( ortholog_one2one ) Mouse_ Bcan ( ortholog_one2one ) Pig_ BCAN ( ortholog_one2one ) Rat_ Bcan ( ortholog_one2one ) Rabbit_ BCAN ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HAPLN1, NCAN, ACAN, HAPLN3, VCAN, HAPLN2, HAPLN4 |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | Expressed in the retina, specifically in the inner nuclear layer, inner plexiform layer and ganglion cell layer (at protein level). {ECO:0000269|PubMed:29777959}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12065791 rs1056695 |
| Subcellular location [CC] | [Isoform 1]: Secreted, extracellular space, extracellular matrix.; [Isoform 2]: Membrane; Lipid-anchor, GPI-anchor. |
| Mouse PG classification | NA |
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