| Gene Information | |
|---|---|
| Gene Name | RTKN |
| Organism | Homo sapiens (Human) |
| Gene Length | 563 |
| Protein Names | Rhotekin |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000114993 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BST9 |
| Gene Card | RTKN |
| Uniprot ID | Q9BST9 |
| Pfam | PF08174; PF00169 |
| In ASD | no |
| Allosteric Prediction | no (-0.198551312) |
| Ortholog in Animals | Alpaca_ RTKN ( ortholog_one2one ) Dog_ RTKN ( ortholog_one2one ) GuineaPig_ RTKN ( ortholog_one2one ) Macaque_ RTKN ( ortholog_one2one ) Mouse_ Rtkn ( ortholog_one2one ) Pig_ RTKN ( ortholog_one2one ) Rat_ Rtkn ( ortholog_one2one ) Rabbit_ RTKN ( ortholog_one2one ) |
| Ohnologs | RTKN2 |
| Paralogs | ANLN, RTKN2 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in prostate, moderately in kidney, heart, brain, spleen, testis, placenta, small intestine, pancreas, skeletal muscle and peripheral blood leukocytes, and weakly in ovary, colon and thymus. Weakly expressed in all normal cell lines tested. Overexpressed in various cancer cell lines. {ECO:0000269|PubMed:10873388, ECO:0000269|PubMed:15480428}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.022222(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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