| Gene Information | |
|---|---|
| Gene Name | FOXP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 715 |
| Protein Names | Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat-containing gene 10 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000128573 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O15409 |
| Gene Card | FOXP2 |
| Uniprot ID | O15409 |
| Pfam | PF00250; PF16159 |
| In ASD | no |
| Allosteric Prediction | no (-0.000492515) |
| Ortholog in Animals | Alpaca_ FOXP2 ( ortholog_one2one ) Dog_ FOXP2 ( ortholog_one2one ) GuineaPig_ FOXP2 ( ortholog_one2one ) Macaque_ FOXP2 ( ortholog_one2one ) Mouse_ Foxp2 ( ortholog_one2one ) Pig_ FOXP2 ( ortholog_one2one ) Rat_ Foxp2 ( ortholog_one2one ) Rabbit_ FOXP2 ( ortholog_one2one ) |
| Ohnologs | FOXP1, FOXP4 |
| Paralogs | FOXG1, FOXI1, FOXF2, FOXP4 |
| Tissue | NA |
| Tissue Specificity | Isoform 1 and isoform 6 are expressed in adult and fetal brain, caudate nucleus and lung. {ECO:0000269|PubMed:12189486}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2A07 (X-ray 1.90A ) 2AS5 (X-ray 2.70A ) |
| DBSNP | rs121908377 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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