Gene Information
Gene NameUNQ779/PRO1573
OrganismHomo sapiens (Human)
Gene Length225
Protein NamesClaudin-8
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBP56748
Gene CardCLDN8
Uniprot IDP56748
PfamPF00822
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in the epididymis, mainly in the caput segment. {ECO:0000269|PubMed:17287494}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs1557294  rs685967  rs686364 
Subcellular location [CC]Cell junction, tight junction {ECO:0000269|PubMed:17287494}. Cell membrane {ECO:0000250|UniProtKB:Q9Z260};
Multi-pass membrane protein {ECO:0000255}. Note=Localizes to tight junctions in all 3 segments of the epididymis, in the caput found in the lateral margins of principal cells, and in the corpus at the interface between basal and principal cells. {ECO:0000269|PubMed:17287494}.
Mouse PG classificationNA
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