| Gene Information | |
|---|---|
| Gene Name | RAD51L2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 376 |
| Protein Names | DNA repair protein RAD51 homolog 3 (R51H3) (RAD51 homolog C) (RAD51-like protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O43502 |
| Gene Card | RAD51C |
| Uniprot ID | O43502 |
| Pfam | PF08423 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in a variety of tissues, with highest expression in testis, heart muscle, spleen and prostate. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002528(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs376403182 rs730881927 rs1555593767 rs267606998 rs61758784 rs267606999 rs28363307 rs35151472 rs587780256 rs587780838 rs28363311 rs267606997 rs149331537 rs147241704 rs1283065191 rs28363317 rs577852020 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:12966089, ECO:0000269|PubMed:16215984}. Cytoplasm {ECO:0000269|PubMed:16215984}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:16215984}. Mitochondrion {ECO:0000269|PubMed:20413593}. Note=DNA damage induces an increase in nuclear levels. Accumulates in DNA damage induced nuclear foci or RAD51C foci which is formed during the S or G2 phase of cell cycle. Accumulation at DNA lesions requires the presence of NBN/NBS1, ATM and RPA. |
| Mouse PG classification | NA |
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