| Gene Information | |
|---|---|
| Gene Name | ARAP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1704 |
| Protein Names | Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 (Centaurin-delta-1) (Cnt-d1) (Protein PARX) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000047365 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q8WZ64 |
| Gene Card | ARAP2 |
| Uniprot ID | Q8WZ64 |
| Pfam | PF01412; PF00169; PF00788; PF00620; PF00536 |
| In ASD | no |
| Allosteric Prediction | no (-0.465298119) |
| Ortholog in Animals | Alpaca_ ARAP2 ( ortholog_one2one ) Dog_ ARAP2 ( ortholog_one2one ) GuineaPig_ ARAP2 ( ortholog_one2one ) Macaque_ ARAP2 ( ortholog_one2one ) Mouse_ Arap2 ( ortholog_one2one ) Pig_ ARAP2 ( ortholog_one2one ) Rat_ Arap2 ( ortholog_one2one ) Rabbit_ ARAP2 ( ortholog_one2one ) |
| Ohnologs | ARAP3, ARAP1 |
| Paralogs | ASAP2, ASAP1, ACAP3, GIT1, ARAP3, AGFG1, ADAP1, SMAP1, AGAP1, ACAP2, AGAP3, AGAP4, AGAP6, AGAP9, AGAP5, ARFGAP1, ASAP3, APPL1, ARFGAP2, ARAP1, AGFG2, APPL2, ARFGAP3, GIT2, ADAP2, SMAP2, AGAP2, ACAP1 |
| Tissue | NA |
| Tissue Specificity | Detected in brain, thymus, lymph node, thyroid, spinal cord, trachea, heart, skeletal muscle, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes. {ECO:0000269|PubMed:11804590}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 1X40 (NMR - ) 2COD (NMR - ) |
| DBSNP | rs35468501 rs35218548 rs4833069 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. |
| Mouse PG classification | NA |
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