| Gene Information | |
|---|---|
| Gene Name | RABIN8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 476 |
| Protein Names | Rab-3A-interacting protein (Rab3A-interacting protein) (Rabin-3) (SSX2-interacting protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96QF0 |
| Gene Card | RAB3IP |
| Uniprot ID | Q96QF0 |
| Pfam | PF06428 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in brain, kidney, heart, pancreas and placenta. Not detected in skeletal muscle or liver. {ECO:0000269|PubMed:12007189, ECO:0000269|PubMed:12221131}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4LHX (X-ray 3.05A ) 4LHY (X-ray 3.10A ) 4LHZ (X-ray 3.20A ) 4UJ3 (X-ray 3.00A ) 4UJ4 (X-ray 4.20A ) 4UJ5 (X-ray 2.60A ) 6F6P (X-ray 2.45A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:12007189, ECO:0000269|PubMed:31467083}. Nucleus {ECO:0000269|PubMed:12007189}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12221131}. Cell projection, lamellipodium. Vesicle {ECO:0000269|PubMed:31467083}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:31467083}. Note=Predominantly cytoplasmic but a small proportion colocalizes with SSX2 in the nucleus. Activation of protein kinase C results in redistribution to the periphery of lamellipodia. {ECO:0000269|PubMed:12007189}. |
| Mouse PG classification | NA |
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