| Gene Information | |
|---|---|
| Gene Name | RABGAP1L |
| Organism | Homo sapiens (Human) |
| Gene Length | 815 |
| Protein Names | Rab GTPase-activating protein 1-like |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000152061 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q5R372 |
| Gene Card | RABGAP1L |
| Uniprot ID | Q5R372 |
| Pfam | PF12473; PF00566 |
| In ASD | no |
| Allosteric Prediction | no (-1.547715654) |
| Ortholog in Animals | Alpaca_ RABGAP1L ( ortholog_one2one ) Dog_ RABGAP1L ( ortholog_one2one ) GuineaPig_ RABGAP1L ( ortholog_one2one ) Macaque_ RABGAP1L ( ortholog_one2one ) Mouse_ Rabgap1l ( ortholog_one2one ) Pig_ RABGAP1L ( ortholog_one2one ) Rat_ Rabgap1l ( ortholog_one2one ) Rabbit_ RABGAP1L ( ortholog_one2one ) |
| Ohnologs | RABGAP1 |
| Paralogs | TBC1D3C, TBC1D3D, TBC1D3, TBC1D3G, TBC1D3B, TBC1D3F, TBC1D3I, TBC1D3E, TBC1D3L, TBC1D3H, TBC1D3K, TBC1D8, TBC1D14, TBC1D10A, SGSM1, TBC1D8B, TBC1D2B, TBC1D10B, RABGAP1, TBC1D17, TBC1D9B, TBC1D25, TBC1D30, TBC1D26, TBC1D28, TBC1D22A, USP6NL, TBC1D9, TBC1D2, TBC1D13, TBC1D12, SGSM2, TBC1D4, GRTP1, EVI5, EVI5L, TBC1D15, SGSM3, TBC1D16, TBCK, TBC1D22B, TBC1D5, TBC1D1, TBC1D10C, TBC1D21 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 3HZJ (X-ray 2.30A ) |
| DBSNP | rs7339904 |
| Subcellular location [CC] | Cytoplasmic vesicle {ECO:0000250|UniProtKB:A6H6A9}. Early endosome {ECO:0000269|PubMed:16923123}. Golgi apparatus {ECO:0000269|PubMed:16923123}. Note=Colocalizes on endosomes partially with EEA1 (PubMed:16923123). Colocalizes and cotransports on motile vesicles with ANK2 (By similarity). {ECO:0000250|UniProtKB:A6H6A9, ECO:0000269|PubMed:16923123}. |
| Mouse PG classification | NA |
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