| Gene Information | |
|---|---|
| Gene Name | CDC25B |
| Organism | Homo sapiens (Human) |
| Gene Length | 580 |
| Protein Names | M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B) |
| Target Name | m-phase inducer phosphatase 2 |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000101224 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P30305 |
| Gene Card | CDC25B |
| Uniprot ID | P30305 |
| Pfam | PF06617; PF00581 |
| In ASD | no |
| Allosteric Prediction | yes (0.497260026) |
| Ortholog in Animals | Alpaca_ CDC25B ( ortholog_one2one ) Dog_ CDC25B ( ortholog_one2one ) GuineaPig_ CDC25B ( ortholog_one2one ) Macaque_ CDC25B ( ortholog_one2one ) Mouse_ Cdc25b ( ortholog_one2one ) Pig_ CDC25B ( ortholog_one2one ) Rat_ Cdc25b ( ortholog_one2one ) |
| Ohnologs | CDC25C, CDC25A |
| Paralogs | CDC25A, CDC25C |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.022121(Chimpanzee);0.027573(Mouse);0.001635(Rat);0.114282(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 1CWR (X-ray 2.10A ) 1CWS (X-ray 2.00A ) 1CWT (X-ray 2.30A ) 1QB0 (X-ray 1.91A ) 1YM9 (X-ray 2.00A ) 1YMD (X-ray 1.70A ) 1YMK (X-ray 1.70A ) 1YML (X-ray 1.70A ) 1YS0 (X-ray 2.00A ) 2A2K (X-ray 1.52A ) 2IFD (X-ray 2.00A ) 2IFV (X-ray 1.60A ) 2UZQ (X-ray 2.38A ) 3FQT (X-ray 1.80A ) 3FQU (X-ray 1.80A ) 4WH7 (X-ray 1.62A ) 4WH9 (X-ray 1.50A ) |
| DBSNP | rs11570019 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:15128871, ECO:0000269|PubMed:15311285, ECO:0000269|PubMed:15908796}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:15908796}. |
| Mouse PG classification | NA |
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