| Gene Information | |
|---|---|
| Gene Name | RAB6C |
| Organism | Homo sapiens (Human) |
| Gene Length | 254 |
| Protein Names | Ras-related protein Rab-6C (Rab6-like protein WTH3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 8 ( ENSG00000222014 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H0N0 |
| Gene Card | RAB6C |
| Uniprot ID | Q9H0N0 |
| Pfam | PF00071 |
| In ASD | no |
| Allosteric Prediction | no (-0.999633943) |
| Ortholog in Animals | NA |
| Ohnologs | RAB6B |
| Paralogs | RAB6D, RAB14, RAB5C, RAB39A, RAB27B, RAB36, RAB33B, RABL2A, RABL2B, RAB27A, RAB3C, RAB5A, RAB15, RAB40AL, RAB3A, RAB40C, RAB12, RAB8A, RAB17, RAB20, RAB24, RAB44, RAB1A, RAB11A, RAB31, RAB7A, IFT27, RAB29, RAB33A, RAB9B, RAB10, RAB4B, RAB32, RAB4A, RAB19, RAB42, RAB9A, RAB40A, RAB11B, RAB2B, RAB2A, RAB43, RAB18, RAB37, RAB25, RASEF, RAB8B, RAB41, RAB40B, RAB21, RAB39B, RAB28, RAB5B, RAB13, RAB38, RAB3B, RAB34, RAB7B, RAB35, RAB3D, RAB1B, RAB6B, RAB22A, RAB26, RAB23, RAB30, RAB6A, DNAJC27 |
| Tissue | NA |
| Tissue Specificity | Highest levels are found in fetal and adult brain, prostate, testis and spinal cord. Undetectable expression in adrenal gland, skeletal muscle, bone marrow, fetal, and adult liver, heart, salivary gland, and trachea. Detected in the HEK293, HEK293T, LNCaP, MCF-7, T-47D and EVSA-T cell lines (at protein level). {ECO:0000269|PubMed:20064528}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs4662674 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:16103095}. Cytoplasm {ECO:0000269|PubMed:16103095}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20064528}. |
| Mouse PG classification | NA |
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