| Gene Information | |
|---|---|
| Gene Name | RAB3GAP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 981 |
| Protein Names | Rab3 GTPase-activating protein catalytic subunit (RAB3 GTPase-activating protein 130 kDa subunit) (Rab3-GAP p130) (Rab3-GAP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000115839 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q15042 |
| Gene Card | RAB3GAP1 |
| Uniprot ID | Q15042 |
| Pfam | PF19533; PF13890 |
| In ASD | no |
| Allosteric Prediction | no (-0.091511792) |
| Ortholog in Animals | Alpaca_ RAB3GAP1 ( ortholog_one2one ) Dog_ RAB3GAP1 ( ortholog_one2one ) GuineaPig_ RAB3GAP1 ( ortholog_one2one ) Macaque_ RAB3GAP1 ( ortholog_one2one ) Mouse_ Rab3gap1 ( ortholog_one2one ) Pig_ RAB3GAP1 ( ortholog_one2one ) Rat_ Rab3gap1 ( ortholog_one2one ) Rabbit_ RAB3GAP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:9030515}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs10445686 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:24891604, ECO:0000269|PubMed:9852129}. Endoplasmic reticulum {ECO:0000269|PubMed:24891604}. Note=In neurons, it is enriched in the synaptic soluble fraction. {ECO:0000269|PubMed:9852129}. |
| Mouse PG classification | LPG |
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