| Gene Information | |
|---|---|
| Gene Name | BCL11B |
| Organism | Homo sapiens (Human) |
| Gene Length | 894 |
| Protein Names | B-cell lymphoma/leukemia 11B (BCL-11B) (B-cell CLL/lymphoma 11B) (COUP-TF-interacting protein 2) (Radiation-induced tumor suppressor gene 1 protein) (hRit1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000127152 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9C0K0 |
| Gene Card | BCL11B |
| Uniprot ID | Q9C0K0 |
| Pfam | PF00096 |
| In ASD | no |
| Allosteric Prediction | no (-0.923434673) |
| Ortholog in Animals | Alpaca_ BCL11B ( ortholog_one2one ) Dog_ BCL11B ( ortholog_one2one ) GuineaPig_ BCL11B ( ortholog_one2one ) Macaque_ BCL11B ( ortholog_one2one ) Mouse_ Bcl11b ( ortholog_one2one ) Pig_ BCL11B ( ortholog_one2one ) Rat_ Bcl11b ( ortholog_one2one ) |
| Ohnologs | BCL11A |
| Paralogs | BCL11A, ZNF217, ZNF516, ZNF536, RREB1, SALL3, SALL2, ZNF831, SALL1, ZNF219, HIVEP2, HIVEP3, SALL4, HIVEP1 |
| Tissue | lymph.node, skin, spleen, tonsil |
| Tissue Specificity | Highly expressed in brain and in malignant T-cell lines derived from patients with adult T-cell leukemia/lymphoma. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs749837100 rs750610248 rs888230251 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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