| Gene Information | |
|---|---|
| Gene Name | RAB18 |
| Organism | Homo sapiens (Human) |
| Gene Length | 206 |
| Protein Names | Ras-related protein Rab-18 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000099246 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NP72 |
| Gene Card | RAB18 |
| Uniprot ID | Q9NP72 |
| Pfam | PF00071 |
| In ASD | no |
| Allosteric Prediction | no (-1.061523699) |
| Ortholog in Animals | Alpaca_ RAB18 ( ortholog_one2one ) Dog_ RAB18 ( ortholog_one2one ) GuineaPig_ RAB18 ( ortholog_one2one ) Macaque_ RAB18 ( ortholog_one2one ) Mouse_ Rab18 ( ortholog_one2one ) Pig_ RAB18 ( ortholog_one2one ) Rat_ AABR07068154.1 ( ortholog_one2many ) Rat_ Rab18 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | RAB14, RAB5C, RAB39A, RAB27B, RAB36, RAB33B, RABL2A, RABL2B, RAB27A, RAB3C, RAB5A, RAB15, RAB40AL, RAB3A, RAB40C, RAB12, RAB8A, RAB17, RAB20, RAB24, RAB44, RAB1A, RAB11A, RAB31, RAB7A, IFT27, RAB29, RAB33A, RAB9B, RAB10, RAB4B, RAB32, RAB4A, RAB19, RAB42, RAB9A, RAB40A, RAB11B, RAB2B, RAB2A, RAB43, RAB37, RAB25, RASEF, RAB6D, RAB6C, RAB8B, RAB41, RAB40B, RAB21, RAB39B, RAB28, RAB5B, RAB13, RAB38, RAB3B, RAB34, RAB7B, RAB35, RAB3D, RAB1B, RAB6B, RAB22A, RAB26, RAB23, RAB30, RAB6A, DNAJC27 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1X3S (X-ray 1.32A ) |
| DBSNP | rs387906832 rs587776875 rs12268932 rs11015859 |
| Subcellular location [CC] | Apical cell membrane {ECO:0000250|UniProtKB:P35293}. Lipid droplet {ECO:0000269|PubMed:23935497, ECO:0000269|PubMed:30970241}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:24891604}. |
| Mouse PG classification | HPG |
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