| Gene Information | |
|---|---|
| Gene Name | LAX1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 398 |
| Protein Names | Lymphocyte transmembrane adapter 1 (Linker for activation of X cells) (Membrane-associated adapter protein LAX) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000122188 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q8IWV1 |
| Gene Card | LAX1 |
| Uniprot ID | Q8IWV1 |
| Pfam | PF15681 |
| In ASD | no |
| Allosteric Prediction | no (-0.517103852) |
| Ortholog in Animals | Alpaca_ LAX1 ( ortholog_one2one ) Dog_ LAX1 ( ortholog_one2one ) GuineaPig_ LAX1 ( ortholog_one2one ) Macaque_ LAX1 ( ortholog_one2one ) Mouse_ Lax1 ( ortholog_one2one ) Pig_ LAX1 ( ortholog_one2one ) Rat_ Lax1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in spleen, thymus, and peripheral blood leukocytes. Expressed in several B-, T-, NK and monocyte cell lines. {ECO:0000269|PubMed:12359715}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:12359715}; Single-pass type III membrane protein {ECO:0000269|PubMed:12359715}. |
| Mouse PG classification | NA |
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