Gene Information
Gene NameRAB17
OrganismHomo sapiens (Human)
Gene Length212
Protein NamesRas-related protein Rab-17
Target NameNA
Target TypeNA
Gene Age382 ( ENSG00000124839 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ9H0T7
Gene CardRAB17
Uniprot IDQ9H0T7
PfamPF00071
In ASDno
Allosteric Predictionno (-1.245788721)
Ortholog in AnimalsAlpaca_ RAB17 ( ortholog_one2one )
Dog_ RAB17 ( ortholog_one2one )
GuineaPig_ RAB17 ( ortholog_one2one )
Macaque_ RAB17 ( ortholog_one2one )
Mouse_ Rab17 ( ortholog_one2one )
Pig_ RAB17 ( ortholog_one2one )
Rat_ Rab17 ( ortholog_one2one )
OhnologsNA
ParalogsRAB14, RAB5C, RAB39A, RAB27B, RAB36, RAB33B, RABL2A, RABL2B, RAB27A, RAB3C, RAB5A, RAB15, RAB40AL, RAB3A, RAB40C, RAB12, RAB8A, RAB20, RAB24, RAB44, RAB1A, RAB11A, RAB31, RAB7A, IFT27, RAB29, RAB33A, RAB9B, RAB10, RAB4B, RAB32, RAB4A, RAB19, RAB42, RAB9A, RAB40A, RAB11B, RAB2B, RAB2A, RAB43, RAB18, RAB37, RAB25, RASEF, RAB6D, RAB6C, RAB8B, RAB41, RAB40B, RAB21, RAB39B, RAB28, RAB5B, RAB13, RAB38, RAB3B, RAB34, RAB7B, RAB35, RAB3D, RAB1B, RAB6B, RAB22A, RAB26, RAB23, RAB30, RAB6A, DNAJC27
TissueNA
Tissue SpecificityExpressed in melanocytes (at protein level). {ECO:0000269|PubMed:21291502}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs3751112  rs34311889  rs2280289 
Subcellular location [CC]Recycling endosome membrane {ECO:0000250|UniProtKB:P35292};
Lipid-anchor {ECO:0000305};
Cytoplasmic side {ECO:0000305}. Melanosome {ECO:0000250|UniProtKB:P35292}. Cell projection, dendrite {ECO:0000250|UniProtKB:P35292}. Note=May also localize at the basolateral and apical plasma membrane. In neurons, localizes to the cell body and dendritic shaft and spine. {ECO:0000250|UniProtKB:P35292}.
Mouse PG classificationNA
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