Gene Information
Gene NameRAB14
OrganismHomo sapiens (Human)
Gene Length215
Protein NamesRas-related protein Rab-14
Target NameNA
Target TypeNA
Gene Age1488 ( ENSG00000119396 )
Evolutionary StageEukaryota
AlphaFoldDBP61106
Gene CardRAB14
Uniprot IDP61106
PfamPF00071
In ASDno
Allosteric Predictionno (-0.281828934)
Ortholog in AnimalsAlpaca_ RAB14 ( ortholog_one2one )
GuineaPig_ RAB14 ( ortholog_one2one )
Macaque_ RAB14 ( ortholog_one2one )
Mouse_ Rab14 ( ortholog_one2one )
Pig_ RAB14 ( ortholog_one2one )
Rat_ Rab14 ( ortholog_one2one )
Rabbit_ RAB14 ( ortholog_one2one )
OhnologsNA
ParalogsRAB5C, RAB39A, RAB27B, RAB36, RAB33B, RABL2A, RABL2B, RAB27A, RAB3C, RAB5A, RAB15, RAB40AL, RAB3A, RAB40C, RAB12, RAB8A, RAB17, RAB20, RAB24, RAB44, RAB1A, RAB11A, RAB31, RAB7A, IFT27, RAB29, RAB33A, RAB9B, RAB10, RAB4B, RAB32, RAB4A, RAB19, RAB42, RAB9A, RAB40A, RAB11B, RAB2B, RAB2A, RAB43, RAB18, RAB37, RAB25, RASEF, RAB6D, RAB6C, RAB8B, RAB41, RAB40B, RAB21, RAB39B, RAB28, RAB5B, RAB13, RAB38, RAB3B, RAB34, RAB7B, RAB35, RAB3D, RAB1B, RAB6B, RAB22A, RAB26, RAB23, RAB30, RAB6A, DNAJC27
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.002419(Rat);0.028571(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1Z0F  (X-ray  2.15A  4D0G  (X-ray  2.50A  4DRZ  (X-ray  2.30A 
DBSNP NA 
Subcellular location [CC]Recycling endosome {ECO:0000269|PubMed:22595670}. Early endosome membrane {ECO:0000269|PubMed:16962593};
Lipid-anchor {ECO:0000305};
Cytoplasmic side {ECO:0000305}. Golgi apparatus membrane {ECO:0000269|PubMed:16962593};
Lipid-anchor {ECO:0000305};
Cytoplasmic side {ECO:0000305}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:16962593};
Lipid-anchor {ECO:0000305};
Cytoplasmic side {ECO:0000305}. Cytoplasmic vesicle, phagosome {ECO:0000269|PubMed:21255211}. Note=Recruited to recycling endosomes by DENND6A (PubMed:22595670). Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). {ECO:0000269|PubMed:21255211, ECO:0000269|PubMed:22595670}.
Mouse PG classificationNA
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