Gene Information | |
---|---|
Gene Name | RAB14 |
Organism | Homo sapiens (Human) |
Gene Length | 215 |
Protein Names | Ras-related protein Rab-14 |
Target Name | NA |
Target Type | NA |
Gene Age | 1488 ( ENSG00000119396 ) |
Evolutionary Stage | Eukaryota |
AlphaFoldDB | P61106 |
Gene Card | RAB14 |
Uniprot ID | P61106 |
Pfam | PF00071 |
In ASD | no |
Allosteric Prediction | no (-0.281828934) |
Ortholog in Animals | Alpaca_ RAB14 ( ortholog_one2one ) GuineaPig_ RAB14 ( ortholog_one2one ) Macaque_ RAB14 ( ortholog_one2one ) Mouse_ Rab14 ( ortholog_one2one ) Pig_ RAB14 ( ortholog_one2one ) Rat_ Rab14 ( ortholog_one2one ) Rabbit_ RAB14 ( ortholog_one2one ) |
Ohnologs | NA |
Paralogs | RAB5C, RAB39A, RAB27B, RAB36, RAB33B, RABL2A, RABL2B, RAB27A, RAB3C, RAB5A, RAB15, RAB40AL, RAB3A, RAB40C, RAB12, RAB8A, RAB17, RAB20, RAB24, RAB44, RAB1A, RAB11A, RAB31, RAB7A, IFT27, RAB29, RAB33A, RAB9B, RAB10, RAB4B, RAB32, RAB4A, RAB19, RAB42, RAB9A, RAB40A, RAB11B, RAB2B, RAB2A, RAB43, RAB18, RAB37, RAB25, RASEF, RAB6D, RAB6C, RAB8B, RAB41, RAB40B, RAB21, RAB39B, RAB28, RAB5B, RAB13, RAB38, RAB3B, RAB34, RAB7B, RAB35, RAB3D, RAB1B, RAB6B, RAB22A, RAB26, RAB23, RAB30, RAB6A, DNAJC27 |
Tissue | NA |
Tissue Specificity | NA |
Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002419(Rat);0.028571(Rabbit) |
Gene Ontology (biological process) |
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Gene Ontology (cellular component) |
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Gene Ontology (molecular function) |
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PDB | 1Z0F (X-ray 2.15A ) 4D0G (X-ray 2.50A ) 4DRZ (X-ray 2.30A ) |
DBSNP | NA |
Subcellular location [CC] | Recycling endosome {ECO:0000269|PubMed:22595670}. Early endosome membrane {ECO:0000269|PubMed:16962593}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Golgi apparatus membrane {ECO:0000269|PubMed:16962593}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:16962593}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cytoplasmic vesicle, phagosome {ECO:0000269|PubMed:21255211}. Note=Recruited to recycling endosomes by DENND6A (PubMed:22595670). Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). {ECO:0000269|PubMed:21255211, ECO:0000269|PubMed:22595670}. |
Mouse PG classification | NA |
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